James William Bryson

This project looks to develop a method that enables researchers to build a mechanistic understanding of how epitranscriptomics shapes gene expression and ultimately cell fate.

Specifically, it looks to explore how mRNA and ribosomal RNA with different modifications choose to pair up to produce varying amounts of protein within different cell types. Armed with this technique I will look to explore the role of a specific combination of modifications in shaping neurogenesis, with much broader applications for dissecting the impact of epitranscriptomic modifications in guiding gene expression programs.