Investigating the RNA-binding defect of RBM5 as a main cause of Neurodegeneration

Assistant Professor

University of Copenhagen

During neurodegeneration, the RNA biology of the brain is affected, which contributes to the disease. Using a highly innovative methodology, we have shown that the main cause may be the deregulation of the RNA-binding protein RBM5. This project aims to investigate this hypothesis by investigating different models of neurodegeneration and patient samples. If its contribution to disease is proven true, RBM5 deregulation could constitute a novel therapeutic target to fight neurodegeneration.

Nicolas Fossat

Investigating the RNA-binding defect of RBM5 as a main cause of Neurodegeneration